Membrane Bound Molecular Machines for Sensing
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چکیده
In this work the construction and dynamic modelling of the Ion Channel Switch (ICS) biosensor is presented. A key feature of the ICS biosensor is that the detection is performed by measuring the timedependent conduction of the engineered tethered membrane which is dependent on the ensemble of aqueous pores and conducting gA dimers present. Using specific molecular components and drive potentials, the ICS can be designed to detect a specific analyte molecules of interest.
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تاریخ انتشار 2014